Ivermectin is a broad-spectrum antiparasitic drug. The active substance of the medicine shows high efficiency against infection with head and pubic lice, scabies, diseases caused by parasites, incl. pinworms, onchocerciasis (“river blindness”), strongyloidiasis, lymphatic filariasis and many others. In some countries, ivermectin is also approved for the treatment of coronavirus infection.
Ivermectin for sale
- Indications: antiparasitic, COVID-19
- Active ingredient: ivermectin
- Brand name: Stromectol Dosage: 3 mg, 6 mg, 12 mg
- Form: pills
- Price: C$ 2.54 per pill
This article contains all the useful information about the drug: uses, dosage, side effects, interactions, warnings. In addition, after reading this guide, you can buy ivermectin (Stromectol) pills online without prescription in our online pharmacy at the lowest price in Canada, as we work directly with the official distributors of pharmaceutical companies.
What is ivermectin used for?
Ivermectin is a chemical from the avermectin group. It is the active ingredient in drug Stromectol. The medication was originally developed for veterinary use in ruminants, dogs and cats. Ivermectin for humans is used for infestations with roundworms, lice, scabies and demodex mites. The medicine leads to paralysis and death of parasites. The pills are usually taken once. As of 2021, ivermectin is also being studied for the treatment of СOVID-19. The drug is available in the form of oral medication and 1% cream.
What is the mechanism of action for ivermectin?
Ivermectin selectively binds to glutamate-driven chloride ion channels in invertebrate muscles and microfilarial nerve cells. As a result of this process, the permeability of the cell membrane for chlorine ions increases, which leads to cell hyperpolarization, paralysis and death of the parasite.
Ivermectin is also thought to act as an agonist for the neurotransmitter gamma-aminobutyric acid (GABA). It disrupts GABA-mediated neurosynaptic transmission in the central nervous system (CNS). Ivermectin also has the ability to inhibit the intrauterine development of helminths.
Ivermectin for COVID-19 treatment
The first reports of the ivermectin effectiveness for COVID-19 treatment appeared in the spring of 2020. Scientists at Australia’s Monash University decided to test whether the substance would help fight Covid-19, as previous laboratory studies have shown that ivermectin is effective against several other viruses, including influenza, dengue and Zika.
In laboratory tests, ivermectin was found to actually have an inhibitory effect on SARS-CoV-2. However, in order to determine the feasibility of its use for the treatment of the disease, additional large-scale studies are needed. At the moment, the European Medicines Agency and the US FDA have spoken out against the use of ivermectin in clinical practice. For the COVID-19 treatment the drug is approved in the Czech Republic, Slovakia and Mexico.
Standard dose Ivermectin for COVID-19 treatment
According to the available data, a higher dose is required for the treatment of COVID-19 than for the treatment of parasitic diseases. The drug is taken at a dosage of 12 mg per day with or after meals for 5 days or until symptoms disappear. Usually, the drug is used in an aggressive course of the disease or in patients with multiple comorbidities and risk factors.
Ivermectin for scabies
This skin condition is caused by an infestation with the mite Sarcoptes scabiei. Symptoms include a rash and intense itching, which is often worse at night. Previously, topical preparations such as creams and ointments were preferably used to combat scabies. However, with the advent of ivermectin tablets, this approach is a thing of the past.
The pill works by disrupting the function of a class of chloride-controlled ligand ion channels in the scabies mite, causing them to open. Ivermectin causes excessive release of the neurotransmitter gamma-aminobutyric acid (GABA) in the parasite’s nervous system, which leads to its death.
Ivermectin pills may be especially effective in treating scabies in immunocompromised patients or when topical therapy has failed. Some doctors recommend simultaneous oral and topical treatments because systemic medications may not effectively penetrate thick, hard areas of skin. In this case, ivermectin cream can also be used.
Ivermectin for lice
Stromectol tablets have been widely and safely used for the treatment of lice in many countries around the world for more than two decades. The drug is used in a single oral dosage of 200 mcg/kg body weight.
A study published in the March 11, 2010 issue of the New England Journal of Medicine found that 95% of those treated with ivermectin were free of lice after two weeks, compared with 85% of those taking other drugs.
In 2012, the FDA also approved Ivermectin lotion to treat head lice. This decision was based on two studies involving 765 adults and children over six months of age. For most patients, it is effective when applied once to dry hair, but it should not be used for repeated treatments without consulting a doctor.
Stromectol for pinworms, onchocerciasis and other parasites
The active substance of the drug has also shown high efficiency in the treatment of diseases caused by various kinds of parasites. Among them are pinworms, onchocerciasis (“river blindness”), strongyloidiasis, lymphatic filariasis and others.
The recommended dose of Stromectol (ivermectin) for pinworms is a single oral dose that provides approximately 200 mcg/kg body weight. Usually, additional doses are not required, but stool control tests should be done to confirm that the infection has been cleared.
The recommended dose of Stromectol for the treatment of onchocerciasis is also a single dose and is approximately 150 mcg/kg of body weight. Reception interval is 12 months. For individual patients, the possibility of re-treatment is allowed at intervals not exceeding 3 months.
Ivermectin for rosacea
Rosacea is an unpleasant condition that includes redness on the nose and cheeks, small inflammatory papules and pustules that cause itching, discomfort, and an unsightly epidermis. In most cases, the cause of its development is the demodex skin mite. Ivermectin cream has been shown to be highly effective in the treatment of rosacea.
In a 12-week clinical study, subjects using ivermectin cream experienced improvement in symptoms in just 2 weeks. During the study, many of the subjects improved their skin appearance.
What dosages does ivermectin come in?
The drug is produced in the form of pills for oral administration. Ivermectin dose for humans – 3 mg, 6 mg, 12 mg. You can also find ivermectin 1% cream, which is used for the topical treatment of scabies, rosacea, etc.
Ivermectin is removed from the bloodstream on average 18 hours after taking the pill. At the same time, it remains in the digestive system and kills parasites for another 12 days.
How to use Stromectol?
The dosage is selected individually, based on the weight, age of the patient and the disease. Always follow the directions in the instructions for the drug, do not exceed the dosage and do not use the medicine more often than you are prescribed.
Take Stromectol on an empty stomach 1 hour before or 2 hours after meals with a full glass of water.
In most cases, the medication is given as a single dose. To effectively treat the infection, you may need to take the drug again several months after the first dose.
If you have a weak immune system due to chronic illness or certain medications, you may need more than one dose of the drug.
To evaluate the effectiveness of therapy, some time after taking the drug, you need to undergo laboratory medical tests (for example, examining stools for the presence of intestinal parasites). When treating “river blindness”, the patient may need a second course of the drug, since ivermectin does not kill adult Onchocerca volvulus worms. The decision in this case is made by the attending physician.
Ivermectin and alcohol
Alcohol consumption can increase the side effects of ivermectin, therefore, during treatment with the drug, it is recommended to reduce the consumption of it to a minimum or completely abandon it.
Is ivermectin safe during pregnancy and lactation?
Although the results of clinical research have found no evidence that ivermectin is harmful to a baby, it is currently discouraged for women to take the medication during pregnancy.
The drug has the ability to pass into breast milk, which means it can harm a baby. It should not be used if you are breastfeeding.
Ivermectin should not be given to children weighing less than 33 lb (15 kg).
Veterinary use of ivermectin
In veterinary medicine, this drug is used to treat parasitic worms in ruminants. Ivermectin is also used to combat parasites in pets: it effectively eliminates itch mites and all sorts of worms in dogs and cats.
How to get ivermectin in Canada?
When some countries approved Stromectol for the treatment of COVID-19, it became more difficult to buy the drug without long waiting times due to the increased demand for it during the pandemic. But our online pharmacy has reliable suppliers of certified medicines, so our customers can purchase ivermectin tablets without long waiting times.
You can purchase the medicine from our online pharmacy. To do this, you just need to add the required number of pills to the basket, and then arrange delivery by mail or directly to your address. Ivermectin is available over the counter in Canada, which makes shopping as easy as possible – you do not need to make an appointment with a doctor and waste time standing in lines.
The ivermectin brand name is marketed under other names such as Heartgard, Sklice and Stromectol in the United States and UK. Ivermectin manufacturer in Canada, pharmaceutical company Merck produces a drug called Mectizan and Stromectol. In the countries of Southeast Asia, the drug is manufactured under the Scabo 6 trademark by Delta Pharma Ltd.
Ivermectin price in Canadian pharmacies
Ivermectin cost is directly proportional to the number of tablets in the package and the dosage you need. You can also purchase generic Stromectol, which is priced well below the original product. This does not in any way affect its effectiveness. Pharmaceutical companies do not need to spend money on the study of an already known substance, so they produce drugs according to an existing proven formula, making them available to a larger number of consumers.
In addition, the cost of drugs on online pharmacies is much cheaper, since it allows sellers to save money needed for logistics, rental of retail space and employee salaries. It is for these reasons that buying online is also much more profitable.
Below are the prices for Stromectol in different dosages:
- Blister of 8 tablets at a dosage of 3 mg – C$39.71
- Blister of 8 tablets with a dosage of 6 mg – C$37.44
- Blister of 10 tablets with a dosage of 12 mg – C$54.47
What are the most common side effects of ivermectin?
In most cases, the drug is well tolerated by the body, however, like all medicines, it can cause a number of unpleasant symptoms. Many of them are natural, because they are the result of the death of parasites, and not a reaction to a drug, and they go away on their own without symptomatic treatment.
Common side effects:
- Headache
- Muscle aches
- Dizziness
- Nausea, diarrhea, vomiting
- Rash, skin redness
This list is not exhaustive, so if you have any concerns after taking Stromectol, seek professional advice.
Similarly, it is recommended to proceed with the development of an allergic reaction. Symptoms include hives, shortness of breath, and swelling of the face, lips, tongue, or throat.
Rare side effects:
- Pain or redness in the eyes
- Severe skin rash, including purulent, itching
- Confusion of consciousness, loss of balance
- Swollen lymph nodes
- Swelling of the hands or feet
- Convulsions
What are the contraindications for ivermectin?
- Allergy to ivermectin
- Serious chronic liver and kidney failure
- Cancer, HIV/AIDS, or other conditions that can weaken the immune system
Interaction with other medicinal products
Ivermectin can interact with some medications and dietary supplements, so always tell your doctor about any other medications, including over-the-counter, vitamins, and herbs you are taking while you are on Stromectol. This can increase the risk of side effects or cause medications to not work properly.
Some drugs that can interact with ivermectin:
- barbiturates
- benzodiazepines
- sodium oxybate
- valproic acid
- warfarin
Interesting facts from the history of the drug
The use of ivermectin has prevented millions of potentially fatal and debilitating infectious diseases. The drug was introduced in 1975 and has been used since1981. Biochemist scientists William Campbell and Satoshi Omura received the 2015 Nobel Prize in Physiology or Medicine for its discovery and application.
Ivermectin for humans is on the World Health Organization’s list of essential medicines. It was approved by the US FDA as an antiparasitic agent in November 1996.
In 2018, ivermectin was the 420th most prescribed drug in the United States, with more than 100,000 prescriptions.
Why you have to order ivermectin in our pharmacy:
- We save your time and money
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- We do not disclose information about you and your order to third parties
- We deliver parcels in opaque packaging, the contents of which only you will know
Buy ivermectin through our online pharmacy and your medicines will be delivered right to your door. We guarantee you a safe purchase and quality service of the highest level. The team of our qualified managers will take care of every detail of your order and answer all your questions and wishes 24/7, including holidays and weekends.